Shirley Ryan AbilityLab receives US Department of Defense grant for clinical study of Integrum’s e-OPRA Implant System

Mölndal, Sweden, March 1st , 2023 – Integrum (publ) (Nasdaq First North Growth Market: INTEG B) today announced that Shirley Ryan AbilityLab – a top-ranked physical medicine and rehabilitation hospital based in Chicago, US – has received a USD 1.5 million grant from the US Department of Defense. The grant will finance a clinical trial to examine the benefits (function, biomechanics, metabolics and user satisfaction) of Integrum’s OPRATM Implant System compared to a traditional socket prosthesis system in three individuals with lower-limb amputations.

Published: 1 March 2023

Shirley Ryan AbilityLab is a global leader in the field of bionics – the study of mechanical systems that mimic parts of living organisms. The US Department of Defense grant, provided through the US Army’s Congressionally Directed Medical Research Program (CDMRP), will be financing the first clinical program in the world combining osseointegration, targeted muscle reinnervation (TMR), and pattern-recognition control to operate a fully powered bionic leg prosthesis, using electromyographic (EMG) sensors.

The clinical study aims to evaluate the comfort and function of Integrum’s OPRATM Implant System compared to socked-based technologies in patients with transfemoral amputations who have received TMR and ambulate with a powered leg prosthesis. Integrum will supply OPRATM implant systems to Shirley Ryan AbilityLab and surgeons at Northwestern Medicine will implant the devices and perform the TMR surgeries.

“The US Department of Defense grant rewarded to Shirley Ryan AbilityLab is a significant recognition, pointing toward the potential of Integrum’s OPRATM Implant System. We are looking forward to contributing to this important initiative that aims to validate our groundbreaking technology and thereby take it yet another step towards the next generation of body-integrated solutions,” comments Rickard Brånemark, CEO of Integrum.

For more information please contact:


Rickard Brånemark, CEO. Phone: +46 708 461061, E-mail: rickard.branemark@integrum.se

Dennis Baecklund, CFO. Phone: +46 (0) 72 556 68 69, E-mail: dennis.baecklund@integrum.se

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