Upgrade your OPRA™ Implant System
to e-OPRA™

Improved and reliable control of your prosthesis that also allows you to feel the world again.

In January 2013, Dr Rickard Brånemark led the world’s first surgery where neuromuscular electrodes were permanently implanted in an amputee, connecting prostheses to the patient’s bone, nerves, and muscles. Today, robotic prostheses controlled via implanted neuromuscular interfaces are about to become a clinical reality thanks to Integrum’s osseointegrated technology. This technology is under development and currently in an ongoing clinical trial, and as soon as it is CE-marked it will be the natural upgrade for people using the OPRA™ Implant System.

An above-elbow OPRA™ Implant System prosthesis holding an egg.


The next generation robotic arm

Conventional robotic prostheses available today are attached with a socket and controlled via electrodes placed on the skin. Robotic prostheses can be very advanced, but such a control system makes them unreliable and limits their functionality, and patients commonly reject them as a result. By connecting the prosthesis directly to bone, nerves and muscles, the Integrum robotic system can provide a significantly improved user experience.

  • Unrestricted range of motion
  • Precise and reliable prosthetic control
  • Direct and intuitive neural sensory feedback
  • Stable mechanical attachment
  • Reduced phantom limb pain

Magnus – a man who made history

Magnus, 42 years old from Haparanda in Northern Sweden, was the first person to receive a prosthesis with a direct connection to bone, nerves and muscles. Thanks to his new robotic arm, Magnus has been able to cope with all the situations he faces in his physically demanding job driving trailers in between Sweden, Norway and Finland.

Read more about Magnus astonishing history:

English article: The Independent
Swedish article: SVT News


Man with an above-elbow e-OPRA™ Implant System prosthesis taking a glass kettle from a shelf.

How does it work?

THE TECHNOLOGY IS built around the OPRA™ Implant System and has been developed in close collaboration with Chalmers University of Technology and Sahlgrenska University Hospital. The artificial arm is directly attached to the skeleton, thus providing mechanical stability. Then the human’s biological control system, that is nerves and muscles, is also interfaced via neuromuscular electrodes to the prosthesis via Integrum’s advanced control system. This creates an intimate union between the body and the prosthesis; between biology and mechatronics.

(A) The prosthetic limb is attached to the abutment, which transfers the load to the bone via the osseointegrated fixture. The abutment screw, which goes through the abutment to the fixture, is designed to maintain the abutment in place. A parallel connector is embedded in the screw’s distal end to electrically interface the artificial limb. This connector is electrically linked to a second feed through connector embedded in the screw’s proximal end. The stack connector interfaced with a pin connector extending from the central sealing component, from which leads extended intramedullary and then transcortically to a final connector located in the soft tissue. The leads from the neuromuscular electrodes are mated to connector.


(B) Intuitive control and sensory feedback enabled by e-OPRA™ Implant System. Control signals to the missing limb are now controlling the prosthesis (green), while sensory input from the prosthesis is transmitted to the patient as it would normally arrive from the missing limb (blue), allowing the patient to feel again.

A perspective drawing of e-OPRA™ Implant System.
An above-elbow e-OPRA™ Implant System connects with human brain.
A perspective drawing of e-OPRA™ Implant System.

Are you interested in participating in a clinical trial?

Are you an amputee who experience problems with conventional socket prostheses? Then the e-OPRA™ Implant System may be applicable for you.